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  • ¡°PARP inhibitor as backbone in ovarian cancer treatment¡±
  • by Eo, Yun-Ho | translator Byun Kyung A | Dec 9, 2020 10:54am
[Interview] Dr. Kim Byoung Gie (Samsung Medical Center) and Dr. Kim Jae Won (SNU Hospital)
¡°Need to start prescribing from first-line maintenance, could use as a backbone for second and later-line therapy¡±
 ¡ã Dr. Kim Byoung Gie (left) and Dr. Kim Jae Won
Disease with limited treatment options tends to simplify the treatment pattern itself. But an emergence of a new treatment mechanism can open doors to various treatment strategies.

A poly ADP-ribose polymerase (PARP) inhibitor is the new mechanism opening the new doors to the ovarian cancer treatment scene.

PARP inhibitors that target BRCA gene like Lynparza (olaparib) and Zejula (niraparib) are indicated as a monotherapy for the maintenance treatment in patients with epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in response (complete or partial) to first and second -line platinum-based chemotherapy, and also as a fourth-line monotherapy in patients, who have been treated with third
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