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  • Ono Pharma Korea¡¯s Braftovi has been approved in Korea
  • by | translator Choi HeeYoung | Aug 24, 2021 06:05am
Combination with Erbitux to treat BRAF V600E mutations identified direct colon cancer
Phase 3 confirm OS improvement compared to Onivyde combination
Ono Pharma Korea announced on the 23rd that it has been approved by the MFDS on the 19th by Braftovi (Encorafenib), a direct bowel cancer treatment.

BRAF inhibitor Braftovi can be used as a combination therapy with Erbitux (Cetuximab) in adult patients with direct colon cancer with previous treatment experience and confirmed BRAF V600E mutation. In Korea, the positive BRAF V600E gene mutation is found in 4.7% of patients with direct bowel cancer. There were no approved drugs based on effectiveness in BRAF gene-variant bowel cancer, requiring a new treatment choice.

This approval is based on the results of BEACON CRC study in patients with non-ablastic progressive or recurrent direct colon cancer showing BRAF V60
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