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  • "MET-targeted therapy as a new personalized NSCLC solution"
  • by Eo, Yun-Ho | translator Alice Kang | Dec 21, 2021 06:05am
Professor Ji-Youn Han, Department of Hemato-oncology, National Cancer Center
¡°Difficulties remain in diagnosis despite use of NGS, etc¡¦ needs improvement "
¡°Expectations rise for EGFR-TKI combo therapies¡¦ does not necessarily need to be used with 3rd generation EGFR-TKIs, 1st or 2nd generation can be enough¡±
 ¡ã Professor Ji-Youn Han
HER2, ALK, EGFR, ROS1, NTRK. These keywords have been frequent visitors in articles on anticancer drugs recently.

With the discovery that effective anticancer treatments differ depending on the patient¡¯s genetic mutation status, personalized treatments that target specific genes of each individual are being introduced. And the development of precision medicine has heralded the paradigm shift of cancer treatments to ¡®gene-specific treatment¡¯ from ¡®diseases-specific treatment.¡¯

Amid rising expectations, the first anticancer treatment that targets the MET gene was newly introduced to Korea. The treatment, Novartis¡¯ ¡®Tabrecta (capmatinib),¡¯ was authorized for the treatment of metastatic non-small cell lung
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