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  • Recommending ezetimibe, ¡°The lower the LDL-C, the better¡±
  • by Eo, Yun-Ho | translator Byun Kyung A | Jan 15, 2020 06:30am
[Interview] Professor Kim Hyo-soo (Seoul National University Department of Internal Medicine)
Believing in ¡®the lower the better¡¯, cholesterol target level will change
Targeting LDL-C level of 55mg/dL needs ezetimibe combination therapy as first-line treatment
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With robust evidences of efficacy, ezetimibe is now one of major options for treating dyslipidemia.

¡°The lower the better.¡± The result of clinical trial IMPROVE-IT, with the slogan claiming the lower the low-density lipoprotein cholesterol (LDL-C) is the better the health benefit, earned its recognition when it was announced in 2015. Numerous pharmaceutical companies in Korea raced each other to release combination drugs with ezetimibe plus either atorvastatin or rosuvastatin. The products landed themselves on the market safe and sound.

Given the positive response, some wondered about the unexpected recommendation addressed in Guidelines for the Management of Dyslipidemia 2018 published by Korean Society of
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