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  • Leclaza and Tagrisso compete for reimb in the first line
  • by Jung, Sae-Im | translator Kim, Jung-Ju | Jul 3, 2023 05:47am
Leclaza¡¯s indication expanded as first-line treatment... company seeks prompt reimbursement for the indication
Tagrisso passes CDDC review after 4 years... is receiving PE evaluations
Leclaza may compete along the same line with Tagrisso if it passes CDDC review in July-Aug,
 ¡ã (From the left) Pic of Leclaza and Tagrisso


Yuhan Corp¡¯s EGFR-targeted anticancer drug ¡®Leclaza (lasertinib)¡¯ has been approved as a first-line treatment in Korea and is competing for reimbursement with its competitor ¡®Tagrisso (osimertinib).¡¯ As reimbursement review for Tagrisso¡¯s first-line indication is already in progress, Yuhan is also expected to hasten its steps to receive reimbursement for its Leclaza.

On June 30th, the Ministry of Food and Drug Safety approved the change in Leclaza¡¯s indication to ¡®the treatment of patients with advanced or metastatic non-small-cell lung cancer harboring EGFR mutation exon 19 deletions or exon 21 substitution.¡¯ With the approval, Leclaza, which had been used as a second-line treatment until now, is now
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