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  • Professor Yoo discovers specific protein expression in HCC
  • by Lee, Tak-Sun | translator Kim, Jung-Ju | Mar 19, 2024 05:45am
Professor Changhoon Yoo, Department of Oncology, Asan Medical Center
Patients with overexpressed TMEM176A/B protein did not respond to immuno-oncology drug + targeted anticancer drug combination therapy
Clinical trial results supported by CMIC Korea were published in an international journal, Nature Medicine
 ¡ã Professor Changhoon Yoo, Department of Oncology, Asan Medical Center
On the 15th, CMIC Korea, a contract research organization (CRO), announced that the results of the RENOBATE (IIT, Phase II) trial led by Professor Changhoon Yoo (Department of Oncology, Asan Medical Center) were recently published in the international academic journal, Nature Medicine (IF=82.9).

This is the first time the results of a clinical study conducted by a Korean researcher have been published in Nature Medicine.

In the RENOBATE 42 patients with hepatocellular carcinoma were administered the immunoconology drug regorafenib in combination with the targeted anticancer drug nivolumab. The study used circulation tumor DNA and single-cell RNA sequencing analysis to identify the characteristics of immune cells
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