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  • Leclaza demonstrates efficacy as combo therapy in NSCLC
  • by Son, Hyung-Min | translator Kang, Shin-Kook | May 27, 2024 05:48am
Will it serve as a green light for its FDA approval as a combination therapy in the US?
Demonstrated improved survival in high-risk groups that have specific biomarkers
Anti-tumor effect confirmed in patients with uncommon mutations, including G719X, L861Q, and S768I

Clinical data demonstrating the efficacy of the Leclaza and Rybrevant combination in lung cancer will be presented at the upcoming American Society of Clinical Oncology (ASCO) Annual Meeting. An abstract published for the ASCO 2024 Annual Meeting (ASCO 2024), a five-day conference that is set to start on the 31st, confirmed the additional efficacy of the combination therapy.

In addition to the primary endpoint results for the combination announced last year, the abstract confirmed the drug¡¯s efficacy in rare types of mutations, giving the combination a green light for its entry into the global new drug market. Johnson & Johnson (J&J), which holds the global rights to both treatments, filed for the combination¡¯
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