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  • Padcev seeks reimb as mono and combo therapy in KOR
  • by Eo, Yun-Ho | translator Alice Kang | Dec 9, 2024 05:47am
Astellas Korea¡¯s new ADC drug for urothelial cancer
Company submits reimbursement applications as first-line and second-line therapy for urothelial cell carcinoma
Whether it will be able to demonstrate cost-effectiveness and expected to bring benefits in combination with Keytruda gains attention
The ADC bladder cancer drug Padcev is seeking reimbursement as both monotherapy and combination therapy in Korea.

According to industry sources, Astellas Pharma Korea recently submitted reimbursement applications for Padcev (enfortumab vedotin) as monotherapy and combination therapy with PD-1 inhibitor Keytruda (pembrolizumab) in the treatment of adult patients with locally advanced or metastatic urothelial carcinoma who have received prior treatment with PD-1 or PD-L1 inhibitors and platinum-based chemotherapy agents.

The monotherapy option passed the Health Insurance Review and Assessment Service's Cancer Disease Deliberation Committee review in February this year, but the application was rejected after the g
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