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  • Handok closer to commercialize new innovative drugs for BTC
  • by Nho, Byung Chul | translator Hong, Ji Yeon | Mar 31, 2025 05:59am
Limited treatment options for biliary tract cancer¡¦a significant unmet medical need for new drugs
Handok shows notable achievements in biliary tract cancer area with its new drug HDB001A
'HDB001A' received fast track designation from the FDA, Phase 2/3 top-line results expected to be announced later in March
Biliary tract cancer (BTC) is known for being difficult to treat. The five-year survival rate is 29.4%, which is the second lowest of all cancer types. Early diagnosis of BTC is difficult, and treatment for BTC is extremely limiting despite of the high risk. Fortunately, the situation is changing. New treatments are being approved in South Korea and new drugs are being developed actively. For instance, Handok's pharmaceuticals are showing potential for treating BTC.

Currently, standardized second-line treatments are not available for BTC when the first-line treatment fails. Due to difficulties in early diagnosis, only 25% of the patients are operable at the diagnosis, and patients show a high recurrence rate of a
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