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  • ¡®Should consider early use of effective new drugs for CML¡¯
  • by Son, Hyung Min | translator Alice Kang | Apr 17, 2025 05:57am
Timothy Hughes, Professor of Hematology, South Australian Health and Medical Research Institute
Although various CML-targeted treatment options have been introduced... More than half the patients develop intolerance
The 4th generation TKI Scemblix introduced¡¦¡¯More than 90% of patients would use it first if there were no restrictions;
 ¡ã Timothy Hughes, Professor of Hematology, South Australian Health and Medical Research Institute
¡°Although various treatment options have emerged for chronic myeloid leukemia (CML), there is still unmet demand, as more than half of patients are intolerant. As CML treatment strategies are shifting to inducing a strong response in the early phase, it is important to prioritize the use of effective drugs.¡±

Timothy Hughes, Professor of Hematology at the South Australian Health and Medical Research Institute, recently gave this assessment regarding CML treatment strategies during an interview with Dailypharm.

The development of various tyrosine kinase inhibitors (TKIs), starting with Novartis' Gleevec, a first-generation targeted anticancer drug, in 2006, then the second-generation treatment options BMS' Spry
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