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  • Mounjaro provides more weight loss than Wegovy
  • by Eo, Yun-Ho | translator Alice Kang | May 13, 2025 06:06am
Lilly¡¯s new obesity drug
Lilly announces results of head-to-head clinical trial SURMOUNT-5
Published in NEJM... Superior to competing drugs in all weight loss reduction goals
Research results found Mounjaro brings more weight loss than its competitor Wegovy.

On the 12th, Lilly announced the detailed results of the SURMOUNT-5 Phase IIIb open-label clinical trial directly comparing Mounjaro (tirzepatide), a dual GIP/GLP-1 receptor agonist, and Wegovy (semaglutide), a GLP-1 receptor agonist.

The study, which compared the weight loss effects of the two drugs that have garnered global attention as obesity treatments, was simultaneously presented at the 32nd European Congress on Obesity (ECO) and published in the international academic journal The New England Journal of Medicine (NEJM).

The study enrolled adult patients with a body mass index (BMI) of 30 kg/m©÷ or higher, or overweigh
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